Variation in Renal Parameters in Dengue and Non-dengue Patients

Background: Dengue virus infection (DVI) is a vector-transmitted illness that is widespread in tropical and subtropical locales. Dengue infection has been linked to numerous renal completely such as proteinuria, glomerulonephritis, and acute kidney injury (AKI), which have been documented to occur concurrently with or immediately following acute dengue infection. The purpose of the study was the variation in renal parameters in dengue and non-dengue patients.

Methods: The retrospective study conducted at cooperative hospital in Vadakara, Kerala in India. Total 100 samples collected (50 dengue patients and 50 Non dengue patients). All dengue patients were identified by registration number using hospital record management system. Patients admitted with primary and confirmed diagnosis of DVI, irrespective of severity were included in this study. The investigation of the study was to compare urea, uric acid, creatinine, and serum electrolyte levels in dengue patients and non-dengue patients. The analysis was performed within 24 hours after collection with the help of ABBOTT ARCHITECT 4100 Analyzer.

Results: In this study 100samples were taken; 50were selected as dengue patients and 50 were selected as non-dengue patients. It has drastically expanded urea and creatinine in dengue patients compared with non-dengue sufferers. Serum electrolytes showed slightly decreased in dengue patients compared with non-dengue sufferers.

Conclusion: The observed change in creatinine and urea increases in dengue patients compared to non-dengue patients. Sodium, potassium and chloride are almost reduced in dengue patients compared to non-dengue patients. Therefore, we can predict acute kidney injury by evaluating the kidney characteristics of dengue patients.