Maxillary Clear Cell Odontogenic Carcinoma - A Rare Entity

Clear cell odontogenic carcinoma (CCOC) is a rare odontogenic tumor with predominance in the posterior mandible, usually occurring in the fifth to seventh decades of life, and being found more commonly in females. It is a potentially aggressive tumour, capable of recurring frequently, locally invasive, and with distant metastases. Here we report a case of clear cell odontogenic carcinoma of maxilla in a 70 years old female, with a tumor mass on right side of the palate in the premolar - molar region. Microscopically, biphasic population of cells with characteristic polygonal, clear cells, hyperchromatic and basaloid cells with eosinophillic cytoplasm were seen. There was positive immunoreactivity with markers Ki67 and cytokeratin CK19. The significance of histochemical and immunohistochemical resources in the correct diagnosis of CCOC is presented.